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They enhance cardiac function, combat heart failure, facilitate myocardial energy uptake, reduce inflammation, alleviate oxidative stress, and inhibit myocardial structural remodeling

At nanomolar concentrations, the tripeptide dampens proinflammatory cytokines: a reduction of IL-8 mRNA by about 35 percent is reported, as well as lower levels of IL-6, IL-12, IFN-gamma and IL-1beta

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